回头看看Beaumont医院一年结果的结论


所有跟贴·加跟贴·新语丝读书论坛

送交者: 羽矢 于 2011-04-23, 15:23:18:

术后导致下肢后遗症,患者生活质量的改善待定,风险收益比待定,唯一亮点是反射弧建立。
指望三年结果能shed more light

CONCLUSIONS
This is the first known North American trial on
lumbar to sacral nerve rerouting to restore bladder
and bowel function in patients with spina bifida.
Although the majority of subjects experienced lower
extremity weakness immediately postoperatively,
most returned to baseline within 12 months. The
exception was 1 patient with a persistent foot drop.
Seven subjects had a reproducible bladder contraction
with stimulation of the appropriate dermatome,
proving the development of a somatic to visceral
reflex. The impact of this surgery on improvement in
quality of life still needs to be determined. This
procedure should remain on a research protocol, and
more patients and longer followup are needed to
understand fully the associated risk/benefit ratio.

REPLY BY AUTHORS
We agree this is a challenging study on many levels.
The intent of publishing these 1-year data was to understand
the potential complications associated with
lumbar to sacral nerve rerouting, demonstrate that a
cutaneous to bladder reflex is achievable and, given
the nationwide interest in this procedure, reinforce the
need to continue this rigorous research protocol until
more is known about the risk-benefit profile. Hopefully
our 36-month data will shed more light on the clinical
usefulness of this innovative procedure.




所有跟贴:


加跟贴

笔名: 密码: 注册笔名请按这里

标题:

内容: (BBCode使用说明